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Pelvic Recurrence After Curative Resection for Rectal Adenocarcinoma: Impact of Surgery on Survival.
Ferrari, Cecilia; Cuniolo, Letizia; Mascherini, Matteo; Santoliquido, Matteo; DI Domenico, Stefano; DE Cian, Franco.
Afiliação
  • Ferrari C; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy ferraricecilia.unige@gmail.com.
  • Cuniolo L; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.
  • Mascherini M; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.
  • Santoliquido M; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.
  • DI Domenico S; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.
  • DE Cian F; Department of General Surgery, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, University of Genoa, Genoa, Italy.
Anticancer Res ; 43(2): 765-771, 2023 Feb.
Article em En | MEDLINE | ID: mdl-36697092
BACKGROUND/AIM: Rectal cancer (RC) represents 30% of colon cancers. Despite the progress achieved in integrated chemoradiotherapy and surgical multidisciplinary treatments, the rate of local recurrence (LR) is 3.7-13%. Multivisceral resections allow many patients with pelvic recurrence to be treated in a curative manner. The purpose of this work is to assess the impact of surgery for rectal cancer patients with pelvic recurrence. PATIENTS AND METHODS: In a retrospective study from 2013 to 2018, data was collected from patients who had undergone rectal resection for adenocarcinoma. We compared perioperative data, postoperative outcomes, oncological results, and survival rates. RESULTS: 106 rectal cancer patients (40-87 years old) requiring surgery were included. The local recurrence rate was 15% (15 patients). LR patients requiring intervention were nine (56%) who underwent sphincter sparing surgeries, and 6 (44%) who underwent surgeries with sphincter resection. There was no statistically significant difference (p=0.416) in the 5-year overall survival rate of patients without recurrence compared to those with pelvic recurrence. CONCLUSION: Curative surgery for local recurrence from rectal cancer is safe and feasible and should be considered in selected cases as it seems to provide acceptable surgical and oncological outcomes.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Adenocarcinoma Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Adenocarcinoma Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article