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Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors.
Kline, Toni; Xu, Cong; Kreitzer, Faith R; Hurst, Dow P; Eldeeb, Khalil M; Wager-Miller, Jim; Olivas, Kathleen; Hepburn, Seon A; Huffman, John W; Mackie, Ken; Howlett, Allyn C; Reggio, Patricia; Stella, Nephi.
Afiliação
  • Kline T; Department of Microbiology, University of Washington, Seattle, WA, 98195, USA.
  • Xu C; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA.
  • Kreitzer FR; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA.
  • Hurst DP; Department of Chemistry and Biochemistry, University of North Carolina, Greensboro, NC, 27412, USA.
  • Eldeeb KM; Department of Physiology and Pharmacology, Wake Forest University, School of Medicine, Winston-Salem, NC, 27157, USA.
  • Wager-Miller J; Department of Psychological and Brain Sciences and the Gill Center, Indiana University, Bloomington, IN, 47405, USA.
  • Olivas K; Department of Microbiology, University of Washington, Seattle, WA, 98195, USA.
  • Hepburn SA; Howard L. Hunter Laboratory, Clemson University, Clemson, SC, 29634, USA.
  • Huffman JW; Howard L. Hunter Laboratory, Clemson University, Clemson, SC, 29634, USA.
  • Mackie K; Department of Psychological and Brain Sciences and the Gill Center, Indiana University, Bloomington, IN, 47405, USA.
  • Howlett AC; Department of Physiology and Pharmacology, Wake Forest University, School of Medicine, Winston-Salem, NC, 27157, USA.
  • Reggio P; Department of Chemistry and Biochemistry, University of North Carolina, Greensboro, NC, 27412, USA.
  • Stella N; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA; Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA, 98195, USA. Electronic address: nstella@uw.edu.
Eur J Med Chem ; 249: 115123, 2023 Mar 05.
Article em En | MEDLINE | ID: mdl-36708677

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabinoides Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabinoides Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article