Substrate stiffness induces nuclear localization of myosin regulatory light chain to suppress apoptosis.

Onishi, Katsuya; Ishihara, Seiichiro; Takahashi, Masayuki; Sakai, Akihiro; Enomoto, Atsushi; Suzuki, Kentaro; Haga, Hisashi

Onishi, Katsuya; Ishihara, Seiichiro; Takahashi, Masayuki; Sakai, Akihiro; Enomoto, Atsushi; Suzuki, Kentaro; Haga, Hisashi.

Afiliação

Onishi K; Division of Soft Matter, Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
Ishihara S; Department of Advanced Transdisciplinary Sciences, Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Takahashi M; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Sakai A; Department of Pathology, Nagoya University Graduate School of Medicine, Japan.
Enomoto A; Department of Pathology, Nagoya University Graduate School of Medicine, Japan.
Suzuki K; Department of Developmental Genetics, Institute of Advanced Medicine, Wakayama Medical University, Japan.
Haga H; Department of Advanced Transdisciplinary Sciences, Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.

FEBS Lett ; 597(5): 643-656, 2023 03.

Article em En | MEDLINE | ID: mdl-36723402

Assuntos

Mecanotransdução Celular; Cadeias Leves de Miosina; Cadeias Leves de Miosina/metabolismo; Fosforilação; Actinas/metabolismo; Apoptose

Palavras-chave

MafB; ZIPK/DAPK3; apoptosis; mechanotransduction; nuclear myosin regulatory light chain (MRLC); substrate stiffness

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cadeias Leves de Miosina / Mecanotransdução Celular Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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