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PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition.
Triscott, Joanna; Reist, Matthias; Küng, Lukas; Mosele, Francielle C; Lehner, Marika; Gallon, John; Ravi, Archna; Arora, Gurpreet K; de Brot, Simone; Lundquist, Mark; Gallart-Ayala, Hector; Ivanisevic, Julijana; Piscuoglio, Salvatore; Cantley, Lewis C; Emerling, Brooke M; Rubin, Mark A.
Afiliação
  • Triscott J; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland.
  • Reist M; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland.
  • Küng L; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland.
  • Mosele FC; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland.
  • Lehner M; Institute of Biosciences, São Paulo State University, São Paulo, Brazil.
  • Gallon J; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland.
  • Ravi A; Visceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Arora GK; Cell and Molecular Biology of Cancer Program, Sanford Burnham Prebys, La Jolla, CA 92037, USA.
  • de Brot S; Cell and Molecular Biology of Cancer Program, Sanford Burnham Prebys, La Jolla, CA 92037, USA.
  • Lundquist M; COMPATH, Institute of Animal Pathology, University of Bern, Bern, Switzerland.
  • Gallart-Ayala H; Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY 10065, USA.
  • Ivanisevic J; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Piscuoglio S; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Cantley LC; Visceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Emerling BM; Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY 10065, USA.
  • Rubin MA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Sci Adv ; 9(5): eade8641, 2023 02 03.
Article em En | MEDLINE | ID: mdl-36724278
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Androgênicos / Neoplasias de Próstata Resistentes à Castração Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Androgênicos / Neoplasias de Próstata Resistentes à Castração Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article