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Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials.
Thomas, Sophie; Embry, Leanne; Walsh, Karin; Bull, Kim; Grundy, Richard; Kennedy, Colin; Lemiere, Jurgen; Hernáiz Driever, Pablo; Limond, Jennifer; Chevignard, Mathilde; Hardy, Kristina.
Afiliação
  • Thomas S; Department of Paediatric Neuropsychology, Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK.
  • Embry L; Child Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Walsh K; Pediatric Hematology/Oncology, UT Health, San Antonio, Texas, USA.
  • Bull K; Division of Pediatric Neuropsychology, Children's National Hospital, Washington, DC, USA.
  • Grundy R; Departments of Psychiatry & Behavioral Medicine and Pediatrics, The George Washington University School of Medicine, Washington, DC, USA.
  • Kennedy C; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, UK.
  • Lemiere J; Department of Paediatric Neuropsychology, Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK.
  • Hernáiz Driever P; Child Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Limond J; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, UK.
  • Chevignard M; Department Oncology, Pediatric Hemato-Oncology, KULeuven, University Hospital Leuven, Leuven, Belgium.
  • Hardy K; Department of Pediatric Oncology and Hematology, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Pediatr Blood Cancer ; 70(5): e30171, 2023 05.
Article em En | MEDLINE | ID: mdl-36734371
ABSTRACT
The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large or multinational trials can be challenging. We provide examples of protocols designed to address this challenge recently employed in clinical trials in the USA and Europe. We discuss their respective strengths and challenges, obstacles encountered and future opportunities for transatlantic collaboration.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncologia / Neoplasias Tipo de estudo: Guideline Limite: Child / Humans País como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncologia / Neoplasias Tipo de estudo: Guideline Limite: Child / Humans País como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article