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Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2' amide-derivatives: Synthesis, biological evaluation and structural studies.
Ghosh, Arun K; Shahabi, Dana; Kipfmiller, Maya; Ghosh, Ajay K; Johnson, Megan; Wang, Yuan-Fang; Agniswamy, Johnson; Amano, Masayuki; Weber, Irene T; Mitsuya, Hiroaki.
Afiliação
  • Ghosh AK; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA. Electronic address: akghosh@purdue.edu.
  • Shahabi D; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Kipfmiller M; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Ghosh AK; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Johnson M; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Wang YF; Department of Biology, Georgia State University, Atlanta, GA 30303, USA.
  • Agniswamy J; Department of Biology, Georgia State University, Atlanta, GA 30303, USA.
  • Amano M; Department of Refractory Viral Diseases, National Center for Global Health and Medicine, Shinjuku, Tokyo 162-8655, Japan; Department of Infectious Diseases, Kumamoto University School of Medicine, Kumamoto 860-8556, Japan.
  • Weber IT; Department of Biology, Georgia State University, Atlanta, GA 30303, USA.
  • Mitsuya H; Department of Refractory Viral Diseases, National Center for Global Health and Medicine, Shinjuku, Tokyo 162-8655, Japan; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch National Cancer Institute, Bethesda, MD 20892, USA; Division of Clinical Sciences, Kumamoto University Hospital
Bioorg Med Chem Lett ; 83: 129168, 2023 03 01.
Article em En | MEDLINE | ID: mdl-36738797
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores da Protease de HIV Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores da Protease de HIV Idioma: En Ano de publicação: 2023 Tipo de documento: Article