Mesenchymal stem cell-derived exosomes regulate microglia phenotypes: a promising treatment for acute central nervous system injury.

Liu, Yu-Yan; Li, Yun; Wang, Lu; Zhao, Yan; Yuan, Rui; Yang, Meng-Meng; Chen, Ying; Zhang, Hao; Zhou, Fei-Hu; Qian, Zhi-Rong; Kang, Hong-Jun

Liu, Yu-Yan; Li, Yun; Wang, Lu; Zhao, Yan; Yuan, Rui; Yang, Meng-Meng; Chen, Ying; Zhang, Hao; Zhou, Fei-Hu; Qian, Zhi-Rong; Kang, Hong-Jun.

Afiliação

Liu YY; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Li Y; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Wang L; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhao Y; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yuan R; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yang MM; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Chen Y; Beidou Precision Medicine Insititute, Guangzhou, Guangdong Province, China.
Zhang H; Beidou Precision Medicine Insititute, Guangzhou, Guangdong Province, China.
Zhou FH; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Qian ZR; Beidou Precision Medicine Insititute, Guangzhou, Guangdong Province, China.
Kang HJ; Medical School of Chinese PLA; Department of Critical Care Medicine, the First Medical Center, Chinese PLA General Hospital, Beijing, China.

Neural Regen Res ; 18(8): 1657-1665, 2023 Aug.

Article em En | MEDLINE | ID: mdl-36751776

Palavras-chave

acute CNS injury; central nervous system inflammation; exosome; immune regulation; mesenchymal stem cell; mesenchymal stem cell-derived exosomes (MSC-Exos); microglia activation; microglia phenotypic transformation; molecular mechanism; neuroinflammation

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article