Targeted lactate dehydrogenase genes silencing in probiotic lactic acid bacteria: A possible paradigm shift in colorectal cancer treatment?

Macharia, John M; Kaposztas, Zsolt; Varjas, Tímea; Budán, Ferenc; Zand, Afshin; Bodnar, Imre; Bence, Raposa L

Macharia, John M; Kaposztas, Zsolt; Varjas, Tímea; Budán, Ferenc; Zand, Afshin; Bodnar, Imre; Bence, Raposa L.

Afiliação

Macharia JM; Doctoral School of Health Sciences, Faculty of Health Science, University of Pecs, City of Pecs, Hungary. Electronic address: johnmacharia@rocketmail.com.
Kaposztas Z; Faculty of Health Sciences, University of Pécs, Hungary.
Varjas T; University of Pecs, Medical School, Department of Public Health Medicine, City of Pecs, Hungary.
Budán F; University of Pecs, Medical School, Institute of Transdisciplinary Discoveries, City of Pecs, Hungary; University of Pécs, Medical School, Institute of Physiology, City of Pécs, Hungary.
Zand A; University of Pecs, Medical School, Department of Public Health Medicine, City of Pecs, Hungary.
Bodnar I; Doctoral School of Health Sciences, Faculty of Health Science, University of Pecs, City of Pecs, Hungary.
Bence RL; Faculty of Health Sciences, University of Pécs, Hungary.

Biomed Pharmacother ; 160: 114371, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36758316

Assuntos

Neoplasias Colorretais; Probióticos; Humanos; L-Lactato Desidrogenase/genética; L-Lactato Desidrogenase/metabolismo; Glicólise; Ácido Láctico/metabolismo; Neoplasias Colorretais/genética; Neoplasias Colorretais/terapia; Probióticos/uso terapêutico; Microambiente Tumoral/genética

Palavras-chave

Cancer management; Colon carcinogenesis; Lactate dehydrogenase A; Lactate dehydrogenase B; Lactic acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Probióticos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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