Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings.

Manyana, Sontaga; Pillay, Melendhran; Gounder, Lilishia; Khan, Aabida; Moodley, Pravi; Naidoo, Kogieleum; Chimukangara, Benjamin

Manyana, Sontaga; Pillay, Melendhran; Gounder, Lilishia; Khan, Aabida; Moodley, Pravi; Naidoo, Kogieleum; Chimukangara, Benjamin.

Afiliação

Manyana S; Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal and National Health Laboratory Service, 800 Vusi Mzimela Road, Durban, 4058, South Africa.
Pillay M; Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal and National Health Laboratory Service, 800 Vusi Mzimela Road, Durban, 4058, South Africa.
Gounder L; Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal and National Health Laboratory Service, 800 Vusi Mzimela Road, Durban, 4058, South Africa.
Khan A; Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal and National Health Laboratory Service, 800 Vusi Mzimela Road, Durban, 4058, South Africa.
Moodley P; Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal and National Health Laboratory Service, 800 Vusi Mzimela Road, Durban, 4058, South Africa.
Naidoo K; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Chimukangara B; CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, South African Medical Research Council (SAMRC), Durban, South Africa.

AIDS Res Ther ; 20(1): 9, 2023 02 09.

Article em En | MEDLINE | ID: mdl-36759801

Assuntos

Infecções por HIV; Integrase de HIV; Soropositividade para HIV; Humanos; Integrases/genética; Integrases/uso terapêutico; Genótipo; Peptídeo Hidrolases/genética; Peptídeo Hidrolases/uso terapêutico; Região de Recursos Limitados; Filogenia; Infecções por HIV/tratamento farmacológico; Mutação; Farmacorresistência Viral/genética; Integrase de HIV/genética

Palavras-chave

Affordable genotypic testing; Drug resistance; HIV-1; Pol gene; Primary integrase resistance; Resource limited settings

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Soropositividade para HIV / Integrase de HIV Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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