Laparoscopic versus open Kasai procedure for biliary atresia: long-term results of a randomized clinical trial.
Pediatr Surg Int
; 39(1): 111, 2023 Feb 10.
Article
em En
| MEDLINE
| ID: mdl-36763200
ABSTRACT
PURPOSE:
The role of the laparoscopic approach for the Kasai procedure in the management of biliary atresia is still controversial. The aim of this study is to compare the long-term results of the laparoscopic Kasai procedure (LKP) to the open Kasai procedure (OKP).METHODS:
A randomized clinical trial was carried out from October 2009 to March 2017. Patients diagnosed with biliary atresia type III were randomized into 2 groups one group underwent LKP and the other group-OKP. All the surgical procedures were performed by the same surgeon with the same technical principles. The long-term outcomes were compared between the two groups.RESULTS:
61 patients underwent LKP and 61 patients-OKP, with a median age at the surgery of 79.7 days. The two groups had no significant differences regarding the patients' baseline characteristics. At follow-up up to 142 months, the jaundice-free rate at the 6th postoperative month for LKP and OKP was 52.5% and 60.7%, respectively (p = 0.23). The 10-year cumulative survival after LKP tended to be inferior to OKP, respectively 44.3% vs. 58.9% (p = 0.09).CONCLUSIONS:
In this study, the long-term results of LKP tended to be inferior compared to OKP although the differences were not significant.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Atresia Biliar
/
Laparoscopia
/
Icterícia
Tipo de estudo:
Observational_studies
Limite:
Humans
/
Infant
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article