Loss of sodium leak channel (NALCN) in the ventral dentate gyrus impairs neuronal activity of the glutamatergic neurons for inflammation-induced depression in male mice.

Wang, Jinping; Yang, Yaoxin; Liu, Jin; Qiu, Jingxuan; Zhang, Donghang; Ou, Mengchan; Kang, Yi; Zhu, Tao; Zhou, Cheng

Wang, Jinping; Yang, Yaoxin; Liu, Jin; Qiu, Jingxuan; Zhang, Donghang; Ou, Mengchan; Kang, Yi; Zhu, Tao; Zhou, Cheng.

Afiliação

Wang J; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Ch
Yang Y; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu J; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Ch
Qiu J; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Ch
Zhang D; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Ou M; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Kang Y; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhu T; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: xwtao.zhu@foxmail.com.
Zhou C; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: zhouc@163.com.

Brain Behav Immun ; 110: 13-29, 2023 05.

Article em En | MEDLINE | ID: mdl-36796706

Assuntos

Giro Denteado; Depressão; Canais Iônicos; Lipopolissacarídeos; Animais; Masculino; Camundongos; Giro Denteado/metabolismo; Giro Denteado/patologia; Depressão/genética; Depressão/metabolismo; Ácido Glutâmico/metabolismo; Inflamação/complicações; Canais Iônicos/metabolismo; Lipopolissacarídeos/farmacologia; Proteínas de Membrana/metabolismo; Neurônios/metabolismo; Sódio/metabolismo

Palavras-chave

Dentate gyrus; Depression; Glutamatergic neurons; Lipopolysaccharide; Sodium leak channel; substance P

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Giro Denteado / Depressão / Canais Iônicos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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