The use of aflibercept (VEGF trap) in mitigating sulfur mustard-induced corneal neovascularization in a rabbit model.

Gore, Ariel; Kadar, Tamar; Cohen, Maayan; Gutman, Hila; Gez, Rellie; Dachir, Shlomit; Horwitz, Vered

Gore, Ariel; Kadar, Tamar; Cohen, Maayan; Gutman, Hila; Gez, Rellie; Dachir, Shlomit; Horwitz, Vered.

Afiliação

Gore A; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Kadar T; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Cohen M; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Gutman H; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Gez R; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Dachir S; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.
Horwitz V; Department. of Pharmacology, Israel Institute for Biological Research, Ness Ziona 74100, Israel.

Toxicol Rep ; 10: 206-215, 2023.

Article em En | MEDLINE | ID: mdl-36825253

Palavras-chave

ANOVA, analysis of variance; Aflibercept; NV, neovascularization; NZW, New Zealand White rabbit; Neovascularization; Ocular chemical insult; Ocular surface; PlGF, placental growth factor; SM, sulfur mustard; Sulfur mustard; TGF-ß, transforming growth factor beta; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article