Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders.

Nirogi, Ramakrishna; Jayarajan, Pradeep; Shinde, Anil; Mohammed, Abdul Rasheed; Grandhi, Venkata Ramalingayya; Benade, Vijay; Goyal, Vinod Kumar; Abraham, Renny; Jasti, Venkat; Cummings, Jeffrey

Nirogi, Ramakrishna; Jayarajan, Pradeep; Shinde, Anil; Mohammed, Abdul Rasheed; Grandhi, Venkata Ramalingayya; Benade, Vijay; Goyal, Vinod Kumar; Abraham, Renny; Jasti, Venkat; Cummings, Jeffrey.

Afiliação

Nirogi R; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Jayarajan P; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Shinde A; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Mohammed AR; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Grandhi VR; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Benade V; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Goyal VK; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Abraham R; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Jasti V; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Cummings J; Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas, NV 89154, USA.

Biomolecules ; 13(2)2023 02 07.

Article em En | MEDLINE | ID: mdl-36830678

Assuntos

Doença de Alzheimer; Serotonina; Animais; Doença de Alzheimer/metabolismo; Receptores de Serotonina/metabolismo; Antagonistas da Serotonina/uso terapêutico

Palavras-chave

5-HT6 receptor antagonist; Alzheimer's disease; SAM-760; agitation; avisetron; cerlapirdine; clinical trials; dementia; idalopirdine; intepirdine; landipirdine; latrepirdine; masupirdine; neuropsychiatric symptoms; psychosis; schizophrenia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serotonina / Doença de Alzheimer Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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