Your browser doesn't support javascript.
loading
Usefulness and Reliability of the Bispectral Index during Balanced Anesthesia for Neurovascular Surgery in New Zealand White Rabbits.
Petrucci, Mariafrancesca; Spadavecchia, Claudia; Wanderer, Stefan; Boillat, Gwendoline; Marbacher, Serge; García Casalta, Luisana Gisela; Casoni, Daniela.
Afiliação
  • Petrucci M; Experimental Surgery Facility (ESF), Department for BioMedical Research, Faculty of Medicine, University of Bern, 3010 Bern, Switzerland.
  • Spadavecchia C; Anesthesiology and Pain Therapy Section, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
  • Wanderer S; Department of Neurosurgery, Kantonsspital Aarau, 5001 Aarau, Switzerland.
  • Boillat G; Cerebrovascular Research Group, Department for BioMedical Research, University of Bern, 3010 Bern, Switzerland.
  • Marbacher S; Department of Neurosurgery, Kantonsspital Aarau, 5001 Aarau, Switzerland.
  • García Casalta LG; Cerebrovascular Research Group, Department for BioMedical Research, University of Bern, 3010 Bern, Switzerland.
  • Casoni D; Department of Neurosurgery, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Brain Sci ; 13(2)2023 Feb 14.
Article em En | MEDLINE | ID: mdl-36831870
Few data about the electroencephalogram and its calculated indices, such as the bispectral index (BIS), have been reported in rabbits. We aimed to evaluate whether a clinically stable anesthesia was mirrored by consistent and stable BIS values and to investigate the effects of modified cerebral blood supply, due to bilateral carotid clamping and re-opening, on BIS values. We also investigated the effects of fentanyl, as an antinociceptive drug, on the BIS. Sixty-eight rabbits undergoing general anesthesia for surgical creation of carotid bifurcation aneurysms were enrolled. The BIS values were recorded at nine selected time points (TPs) during each procedure and before and after fentanyl administration. The BIS values over time were compared with two-way repeated-measures analysis of variance followed by Tukey test, while the Wilcoxon signed rank test was performed to compare values at clamping and re-opening of the carotids as well as before and after fentanyl administration. The BIS values were significantly lower during anesthesia than at the end of anesthesia and at tracheal extubation; no significant differences were found among other TPs. Adequate depth of anesthesia was mirrored by consistent BIS values among rabbits, and alteration of cerebral blood supply did not modify BIS values, except once. Following fentanyl, BIS values did not change in a clinically relevant way.
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article