Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective.
Int J Mol Sci
; 24(4)2023 Feb 20.
Article
em En
| MEDLINE
| ID: mdl-36835600
ABSTRACT
Domain of unknown function (DUF) is a general term for many uncharacterized domains with two distinct features relatively conservative amino acid sequence and unknown function of the domain. In the Pfam 35.0 database, 4795 (24%) gene families belong to the DUF type, yet, their functions remain to be explored. This review summarizes the characteristics of the DUF protein families and their functions in regulating plant growth and development, generating responses to biotic and abiotic stress, and other regulatory roles in plant life. Though very limited information is available about these proteins yet, by taking advantage of emerging omics and bioinformatic tools, functional studies of DUF proteins could be utilized in future molecular studies.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas
/
Biologia Computacional
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article