Mechanism of Action and Structure-Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor.

Dengler, Daniela G; Harikumar, Kaleeckal G; Yen, Alice; Sergienko, Eduard A; Miller, Laurence J

Dengler, Daniela G; Harikumar, Kaleeckal G; Yen, Alice; Sergienko, Eduard A; Miller, Laurence J.

Afiliação

Dengler DG; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Harikumar KG; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ 85259, USA.
Yen A; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Sergienko EA; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Miller LJ; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ 85259, USA.

Membranes (Basel) ; 13(2)2023 Jan 24.

Article em En | MEDLINE | ID: mdl-36837653