Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit.
Antimicrob Agents Chemother
; 67(3): e0113022, 2023 03 16.
Article
em En
| MEDLINE
| ID: mdl-36853002
ABSTRACT
We report the first identification of a fluconazole-resistant Candida parapsilosis (FR-Cp) strain in our hospital, which subsequently caused an outbreak involving 17 patients (12 deaths) within a 26-bed French intensive care unit. Microsatellite genotyping confirmed that all FR-Cp isolates belonged to the same clone. Given recent reports of rapid dissemination of these emerging clones, routine testing of azole susceptibility for all Candida parapsilosis isolates should be encouraged, at least in ICU patients.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fluconazol
/
Candida parapsilosis
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article