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New insights into the inhibitory effect of phenol carboxylic acid antioxidants on mushroom tyrosinase by molecular dynamic studies and experimental assessment.
Shojazadeh, Tahereh; Zolghadr, Leila; Gharaghani, Sajjad; JafarKhani, Saeed; Molaabasi, Fatemeh; Piri, Hossein; Gheibi, Nematollah.
Afiliação
  • Shojazadeh T; Department of Clinical Biochemistry and Genetic, Qazvin University of Medical Sciences, Qazvin, Iran.
  • Zolghadr L; Department of Chemistry, Imam Khomeini International University, Qazvin, Iran.
  • Gharaghani S; Laboratory of Bioinformatics and Drug Design, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
  • JafarKhani S; Division of Biomedical Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran.
  • Molaabasi F; Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran.
  • Piri H; Biomaterials and Tissue Engineering Research Group, Department of Interdisciplinary Technologies, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
  • Gheibi N; Cellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
J Biomol Struct Dyn ; 41(22): 13404-13414, 2023.
Article em En | MEDLINE | ID: mdl-36856125
In silico study Ferulic and Chlorogenic Acids was performed to check the binding profile against tyrosinase.Investigate the inhibitory It inhibited tyrosinase in a competitive manner.Ferulic and Chlorogenic fatty acids for prevention of medical hyperpigmentation, and it is a good candidate for cosmetic applications.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monofenol Mono-Oxigenase / Agaricales Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monofenol Mono-Oxigenase / Agaricales Idioma: En Ano de publicação: 2023 Tipo de documento: Article