Persistently expressed human chorionic gonadotropin induces premature luteinization and progressive alterations on the reproductive axis in female mice.

Marcial Lopez, Agustina; Ratner, Laura D; Martinez, Carolina S; Di Giorgio, Noelia; Poutanen, Matti; Huhtaniemi, Ilpo T; Rulli, Susana B

Marcial Lopez, Agustina; Ratner, Laura D; Martinez, Carolina S; Di Giorgio, Noelia; Poutanen, Matti; Huhtaniemi, Ilpo T; Rulli, Susana B.

Afiliação

Marcial Lopez A; Instituto de Biología y Medicina Experimental-CONICET, Vuelta de Obligado 2490 (1428), Buenos Aires, Argentina.
Ratner LD; Instituto de Biología y Medicina Experimental-CONICET, Vuelta de Obligado 2490 (1428), Buenos Aires, Argentina.
Martinez CS; Laboratorio de Bio-nanotecnología, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Grupo vinculado GBEyB, IMBICE-CONICET-CICPBA, Bernal, Argentina.
Di Giorgio N; Instituto de Biología y Medicina Experimental-CONICET, Vuelta de Obligado 2490 (1428), Buenos Aires, Argentina.
Poutanen M; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; Turku Center for Disease Modeling, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland.
Huhtaniemi IT; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London W12 0NN, UK
Rulli SB; Instituto de Biología y Medicina Experimental-CONICET, Vuelta de Obligado 2490 (1428), Buenos Aires, Argentina. Electronic address: rulli.susana@maimonides.edu.

Gen Comp Endocrinol ; 336: 114247, 2023 05 15.

Article em En | MEDLINE | ID: mdl-36858273

Assuntos

Gonadotropina Coriônica; Infertilidade; Humanos; Camundongos; Feminino; Animais; Gonadotropina Coriônica/farmacologia; Gonadotropina Coriônica Humana Subunidade beta/genética; Gonadotropina Coriônica Humana Subunidade beta/metabolismo; Camundongos Transgênicos; Luteinização; Mamíferos/metabolismo

Palavras-chave

Female reproduction; Human chorionic gonadotropin; Ovary; Premature luteinization; Prolactin; Transgenic mice

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gonadotropina Coriônica / Infertilidade Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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