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Fetal Cardiac Cine MRI with Doppler US Gating in Complex Congenital Heart Disease.
Vollbrecht, Thomas M; Hart, Christopher; Zhang, Shuo; Katemann, Christoph; Isaak, Alexander; Pieper, Claus C; Kuetting, Daniel; Faridi, Bettina; Strizek, Brigitte; Attenberger, Ulrike; Kipfmueller, Florian; Herberg, Ulrike; Geipel, Annegret; Luetkens, Julian A.
Afiliação
  • Vollbrecht TM; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Hart C; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Zhang S; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Katemann C; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Isaak A; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Pieper CC; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Kuetting D; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Faridi B; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Strizek B; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Attenberger U; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Kipfmueller F; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Herberg U; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Geipel A; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
  • Luetkens JA; Departments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1,
Radiol Cardiothorac Imaging ; 5(1): e220129, 2023 Feb.
Article em En | MEDLINE | ID: mdl-36860838
ABSTRACT

Purpose:

To apply Doppler US (DUS)-gated fetal cardiac cine MRI in clinical routine and investigate diagnostic performance in complex congenital heart disease (CHD) compared with that of fetal echocardiography. Materials and

Methods:

In this prospective study (May 2021 to March 2022), women with fetuses with CHD underwent fetal echocardiography and DUS-gated fetal cardiac MRI on the same day. For MRI, balanced steady-state free precession cine images were acquired in the axial and optional sagittal and/or coronal orientations. Overall image quality was assessed on a four-point Likert scale (from 1 = nondiagnostic to 4 = good image quality). The presence of abnormalities in 20 fetal cardiovascular features was independently assessed by using both modalities. The reference standard was postnatal examination results. Differences in sensitivities and specificities were determined by using a random-effects model.

Results:

The study included 23 participants (mean age, 32 years ± 5 [SD]; mean gestational age, 36 weeks ± 1). Fetal cardiac MRI was completed in all participants. The median overall image quality of DUS-gated cine images was 3 (IQR, 2.5-4). In 21 of 23 participants (91%), underlying CHD was correctly assessed by using fetal cardiac MRI. In one case, the correct diagnosis was made by using MRI only (situs inversus and congenitally corrected transposition of the great arteries). Sensitivities (91.8% [95% CI 85.7, 95.1] vs 93.6% [95% CI 88.8, 96.2]; P = .53) and specificities (99.9% [95% CI 99.2, 100] vs 99.9% [95% CI 99.5, 100]; P > .99) for the detection of abnormal cardiovascular features were comparable between MRI and echocardiography, respectively.

Conclusion:

Using DUS-gated fetal cine cardiac MRI resulted in performance comparable with that of using fetal echocardiography for diagnosing complex fetal CHD.Keywords Pediatrics, MR-Fetal (Fetal MRI), Cardiac, Heart, Congenital, Fetal Imaging, Cardiac MRI, Prenatal, Congenital Heart DiseaseClinical trial registration no. NCT05066399 Supplemental material is available for this article. © RSNA, 2023See also the commentary by Biko and Fogel in this issue.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article