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Healthy Vaccinee Bias and MenB-FHbp Vaccine Effectiveness Against Gonorrhea.
Abara, Winston E; Bernstein, Kyle T; Lewis, Felicia M T; Pathela, Preeti; Islam, Aras; Eberhart, Michael; Cheng, Iris; Ternier, Alexandra; Sanderson Slutsker, Jennifer; Madera, Robbie; Kirkcaldy, Robert.
Afiliação
  • Abara WE; From the Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
  • Bernstein KT; From the Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
  • Pathela P; Bureaus of STI.
  • Islam A; Philadelphia Department of Public Health, Philadelphia, PA.
  • Eberhart M; Philadelphia Department of Public Health, Philadelphia, PA.
  • Cheng I; Immunization, New York City Department of Health and Mental Hygiene, New York City, NY.
  • Ternier A; Immunization, New York City Department of Health and Mental Hygiene, New York City, NY.
  • Sanderson Slutsker J; Bureaus of STI.
  • Madera R; Philadelphia Department of Public Health, Philadelphia, PA.
  • Kirkcaldy R; From the Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Sex Transm Dis ; 50(6): e8-e10, 2023 06 01.
Article em En | MEDLINE | ID: mdl-36863060
ABSTRACT: Observational studies demonstrated 30% to 40% effectiveness of outer-membrane vesicle (OMV) meningococcal serogroup B vaccines against gonorrhea. To explore whether healthy vaccinee bias influenced such findings, we examined the effectiveness of MenB-FHbp, a non-OMV vaccine that is not protective against gonorrhea. MenB-FHbp was ineffective against gonorrhea. Healthy vaccinee bias likely did not confound earlier studies of OMV vaccines.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gonorreia / Vacinas Meningocócicas / Neisseria meningitidis Sorogrupo B Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gonorreia / Vacinas Meningocócicas / Neisseria meningitidis Sorogrupo B Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article