[Thrombophilic study in dialysis patients].
G Ital Nefrol
; 40(1)2023 Feb 27.
Article
em It
| MEDLINE
| ID: mdl-36883923
ABSTRACT
Chronic kidney disease is a complex phenotype that results from the association of underlying kidney disease and environmental and genetic factors. In addition to the traditional risk factors, genetic factors are involved in the etiology of renal disease, including single nucleotide polymorphisms which could account for the increased mortality from cardiovascular disease of our hemodialysis patients. The genes that influence the development and rate of progression of kidney disease deserve to be better defined. We have evaluated the alterations of thrombophilia genes in hemodialysis patients and in blood donors and we have compared the results obtained. The objective of the present study is to identify biomarkers of morbidity and mortality, which allow us to identify patients with chronic kidney disease at high risk, thanks to which it is possible to implement accurate therapeutic strategies and preventive strategies that have the objective of intensifying controls in these patients.
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Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Trombofilia
/
Insuficiência Renal Crônica
/
Falência Renal Crônica
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
It
Ano de publicação:
2023
Tipo de documento:
Article