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Entrectinib dose confirmation in pediatric oncology patients: pharmacokinetic considerations.
Meneses-Lorente, Georgina; Guerini, Elena; Mercier, Francois; Parrott, Neil; Kowalski, Karey; Chow-Maneval, Edna; Buchheit, Vincent; Bergthold, Guillaume; Fox, Elizabeth; Phipps, Alex; Djebli, Nassim.
Afiliação
  • Meneses-Lorente G; Pharma Research and Early Development, Roche Products Ltd., Welwyn Garden City, UK. georgina.meneses-lorente@roche.com.
  • Guerini E; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Mercier F; Biostatistics, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Parrott N; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Kowalski K; PharmD Clinical Pharmacology, Ignyta, Inc., San Diego, CA, USA.
  • Chow-Maneval E; Clinical Development, Ignyta, Inc., San Diego, CA, USA.
  • Buchheit V; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Bergthold G; Product Development Oncology and Hematology Department, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Fox E; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Phipps A; Department of Clinical Pharmacology, Roche Innovation Center Welwyn, Roche Products Ltd., Welwyn Garden City, UK.
  • Djebli N; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Cancer Chemother Pharmacol ; 91(3): 239-246, 2023 03.
Article em En | MEDLINE | ID: mdl-36884068
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Neoplasias Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Neoplasias Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article