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Phosphorylation of KRT8 (keratin 8) by excessive mechanical load-activated PKN (protein kinase N) impairs autophagosome initiation and contributes to disc degeneration.
Wang, Di; Shang, Qiliang; Mao, Jianxin; Gao, Chu; Wang, Jie; Wang, Dong; Wang, Han; Jia, Haoruo; Peng, Pandi; Du, Mu; Luo, Zhuojing; Yang, Liu.
Afiliação
  • Wang D; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Shang Q; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Mao J; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Gao C; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Wang J; Medical Research Institute, Northwestern Polytechnical University, Xi'an, People's Republic of China.
  • Wang D; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Wang H; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Jia H; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Peng P; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Du M; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
  • Luo Z; Medical Research Institute, Northwestern Polytechnical University, Xi'an, People's Republic of China.
  • Yang L; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
Autophagy ; 19(9): 2485-2503, 2023 09.
Article em En | MEDLINE | ID: mdl-36897022
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Degeneração do Disco Intervertebral Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Degeneração do Disco Intervertebral Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article