Oral Bioactive Self-Nanoemulsifying Drug Delivery Systems of Remdesivir and Baricitinib: A Paradigmatic Case of Drug Repositioning for Cancer Management.

Kazi, Mohsin; Alanazi, Yousef; Kumar, Ashok; Shahba, Ahmad Abdul-Wahhab; Rizwan Ahamad, Syed; Alghamdi, Khalid M

Kazi, Mohsin; Alanazi, Yousef; Kumar, Ashok; Shahba, Ahmad Abdul-Wahhab; Rizwan Ahamad, Syed; Alghamdi, Khalid M.

Afiliação

Kazi M; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alanazi Y; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Kumar A; Vitiligo Research Chair, Department of Dermatology, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.
Shahba AA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Rizwan Ahamad S; Kayyali Research Chair for Pharmaceutical Industries, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alghamdi KM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Molecules ; 28(5)2023 Feb 28.

Article em En | MEDLINE | ID: mdl-36903483

Assuntos

Neoplasias da Mama; Neoplasias Pulmonares; Nanopartículas; Humanos; Feminino; Reposicionamento de Medicamentos; Administração Oral; Emulsões; Sistemas de Liberação de Medicamentos/métodos; Solubilidade; Óleos; Tamanho da Partícula; Disponibilidade Biológica; Tensoativos; Liberação Controlada de Fármacos

Palavras-chave

A549 lung cancer cells; MDA-MB-231 breast cancer cells; bioactive self-nanoemulsifying drug delivery systems (bio-SNEDDS); cytotoxicity; natural oils

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Nanopartículas / Neoplasias Pulmonares Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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