SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS.

Lin, Xiaohu; Pang, Qianqian; Hu, Jie; Sun, Jiaqi; Dai, Siya; Yu, Yijia; Xu, Jinghong

Lin, Xiaohu; Pang, Qianqian; Hu, Jie; Sun, Jiaqi; Dai, Siya; Yu, Yijia; Xu, Jinghong.

Afiliação

Lin X; Department of Plastic and Reconstructive Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Pang Q; Ningbo Hwamei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China.
Hu J; Department of Plastic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Sun J; Department of Plastic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Dai S; Department of Plastic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yu Y; Department of Plastic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xu J; Department of Plastic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

J Cell Mol Med ; 27(8): 1045-1055, 2023 04.

Article em En | MEDLINE | ID: mdl-36916534

Assuntos

Proteínas Ativadoras de GTPase; Queloide; Proteína Smad4; Humanos; Transporte Ativo do Núcleo Celular; Núcleo Celular/metabolismo; Proteínas Ativadoras de GTPase/metabolismo; Queloide/metabolismo; Proteína Smad4/genética; Proteína Smad4/metabolismo; Sumoilação

Palavras-chave

CRM1; RanGAP1*SUMO1; Smad4; nuclear export; nucleocytoplasmic transport; sumoylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Ativadoras de GTPase / Proteína Smad4 / Queloide Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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