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Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance.
Spielvogel, Ean; Lee, Sook-Kyung; Zhou, Shuntai; Lockbaum, Gordon J; Henes, Mina; Sondgeroth, Amy; Kosovrasti, Klajdi; Nalivaika, Ellen A; Ali, Akbar; Yilmaz, Nese Kurt; Schiffer, Celia A; Swanstrom, Ronald.
Afiliação
  • Spielvogel E; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Lee SK; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Zhou S; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Lockbaum GJ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Henes M; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
  • Sondgeroth A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
  • Kosovrasti K; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Nalivaika EA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States.
  • Ali A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
  • Yilmaz NK; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
  • Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
  • Swanstrom R; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, United States.
Elife ; 122023 03 15.
Article em En | MEDLINE | ID: mdl-36920025

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Inibidores da Protease de HIV Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Inibidores da Protease de HIV Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article