Computational tools for exploring peptide-membrane interactions in gram-positive bacteria.
Comput Struct Biotechnol J
; 21: 1995-2008, 2023.
Article
em En
| MEDLINE
| ID: mdl-36950221
3-HBA, 3Hydroxybenzoic Acid; AAC, Amino Acid Composition; ABC, ATP-binding cassette; ACD, Available Chemicals Database; AIP, Autoinducing Peptide; AMP, Anti-Microbial Peptide; ATP, Adenosine Triphosphate; Agr, Accessory gene regulator; BFE, Binding Free Energy; BIP Inhibitors; BIP, Biofilm Inhibitory Peptides; BLAST, Basic Local Alignment Search Tool; BNB, Bernoulli Naïve-Bayes; CADD, Computer-Aided Drug Design; CSP, Competence Stimulating Peptide; CTD, Composition-Transition-Distribution; D, Aspartate; DCH, 3,3'-(3,4-dichlorobenzylidene)-bis-(4-hydroxycoumarin); DT, Decision Tree; FDA, Food and Drug Administration; GBM, Gradient Boosting Machine; GDC, g-gap Dipeptide; GNB, Gaussian NB; Gram-positive bacteria; H, Histidine; H-Kinase, Histidine Kinase; H-phosphotransferase, Histidine Phosphotransferase; HAM, Hamamelitannin; HGM, Human Gut Microbiota; HNP, Human Neutrophil Peptide; IT, Information Theory Features; In silico approaches; KNN, K-Nearest Neighbors; MCC, Mathew Co-relation Coefficient; MD, Molecular Dynamics; MDR, Multiple Drug Resistance; ML, Machine Learning; MRSA, Methicillin Resistant S. aureus; MSL, Multiple Sequence Alignment; OMR, Omargliptin; OVP, Overlapping Property Features; PCP, Physicochemical Properties; PDB, Protein Data Bank; PPIs, Protein-Protein Interactions; PSM, Phenol-Soluble Modulin; PTM, Post Translational Modification; QS, Quorum Sensing; QSCN, QS communication network; QSHGM, Quorum Sensing of Human Gut Microbes; QSI, QS Inhibitors; QSIM, QS Interference Molecules; QSP inhibitors; QSP predictors; QSP, QS Peptides; QSPR, Quantitative Structure Property Relationship; Quorum sensing peptides; RAP, RNAIII-activating protein; RF, Random Forest; RIP, RNAIII-inhibiting peptide; ROC, Receiver Operating Characteristic; SAR, Structure-Activity Relationship; SFS, Sequential Forward Search; SIT, Sitagliptin; SVM, Support Vector Machine; TCS, Two-Component Sensory; TRAP, Target of RAP; TRG, Trelagliptin; WHO, World Health Organization; mRMR, minimum Redundancy and Maximum Relevance
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MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article