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Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses.
Karlov, Dmitry S; Long, Sarah L; Zeng, Ximin; Xu, Fuzhou; Lal, Kanhaya; Cao, Liu; Hayoun, Karim; Lin, Jun; Joyce, Susan A; Tikhonova, Irina G.
Afiliação
  • Karlov DS; School of Pharmacy, Medical Biology Centre, Queen's University Belfast, BT9 7BL Northern Ireland, UK.
  • Long SL; School of Biochemistry and Cell Biology, University College Cork, Cork T12 YT20, Ireland; APC Microbiome Ireland, University College Cork, Cork T12 YT20, Ireland.
  • Zeng X; Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA.
  • Xu F; Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
  • Lal K; School of Pharmacy, Medical Biology Centre, Queen's University Belfast, BT9 7BL Northern Ireland, UK.
  • Cao L; Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA.
  • Hayoun K; School of Biochemistry and Cell Biology, University College Cork, Cork T12 YT20, Ireland; APC Microbiome Ireland, University College Cork, Cork T12 YT20, Ireland.
  • Lin J; Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA. Electronic address: jlin6@utk.edu.
  • Joyce SA; School of Biochemistry and Cell Biology, University College Cork, Cork T12 YT20, Ireland; APC Microbiome Ireland, University College Cork, Cork T12 YT20, Ireland. Electronic address: s.joyce@ucc.ie.
  • Tikhonova IG; School of Pharmacy, Medical Biology Centre, Queen's University Belfast, BT9 7BL Northern Ireland, UK. Electronic address: i.tikhonova@qub.ac.uk.
Structure ; 31(5): 629-638.e5, 2023 05 04.
Article em En | MEDLINE | ID: mdl-36963397
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Amidoidrolases Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Amidoidrolases Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article