Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2.

Xie, Qinya; Bozzo, Caterina Prelli; Eiben, Laura; Noettger, Sabrina; Kmiec, Dorota; Nchioua, Rayhane; Niemeyer, Daniela; Volcic, Meta; Lee, Jung-Hyun; Zech, Fabian; Sparrer, Konstantin M J; Drosten, Christian; Kirchhoff, Frank

Xie, Qinya; Bozzo, Caterina Prelli; Eiben, Laura; Noettger, Sabrina; Kmiec, Dorota; Nchioua, Rayhane; Niemeyer, Daniela; Volcic, Meta; Lee, Jung-Hyun; Zech, Fabian; Sparrer, Konstantin M J; Drosten, Christian; Kirchhoff, Frank.

Afiliação

Xie Q; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Bozzo CP; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Eiben L; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Noettger S; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Kmiec D; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Nchioua R; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Niemeyer D; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Volcic M; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Lee JH; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Zech F; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Sparrer KMJ; Institute of Molecular Virology, Ulm University Medical Centre, 89081 Ulm, Germany.
Drosten C; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Kirchhoff F; German Centre for Infection Research (DZIF), Associated Partner Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.