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Association between time-restricted eating and non-alcoholic fatty liver disease in a nationwide cross-sectional study.
Zeng, Xueke; Xie, Shaoyu; Jiang, Fei; Li, Xiude; Li, Meiling; Zhang, Tengfei; Zhang, Yaozong; Rao, Songxian; Mo, Yufeng; Zhang, Honghua; Ye, Shu; Liu, Mengfei; Li, Haowei; Zhu, Yu; Huang, Yong; Wang, Danni; Yang, Wanshui.
Afiliação
  • Zeng X; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Xie S; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, Hefei230032, Anhui, People's Republic of China.
  • Jiang F; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei230032, Anhui, People's Republic of China.
  • Li X; Anhui Provincial Key Laboratory of Population Health and Aristogenics/Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei, Anhui, People's Republic of China.
  • Li M; Department of Chronic Non-communicable Diseases Prevention and Control, Lu'an Municipal Center for Disease Control and Prevention, Lu'an, Anhui, People's Republic of China.
  • Zhang T; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Zhang Y; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Rao S; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Mo Y; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Zhang H; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Ye S; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Liu M; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Li H; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Zhu Y; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Huang Y; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Wang D; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
  • Yang W; Department of Nutrition, School of Public Health, Anhui Medical University, Hefei230032, Anhui, People's Republic of China.
Br J Nutr ; 130(10): 1787-1794, 2023 11 28.
Article em En | MEDLINE | ID: mdl-36971368
The association between time-restricted eating (TRE) and the risk of non-alcoholic fatty liver disease (NAFLD) is less studied. Moreover, whether the association is independent of physical exercise or diet quality or quantity is uncertain. In this nationwide cross-sectional study of 3813 participants, the timing of food intakes was recorded by 24-h recalls; NAFLD was defined through vibration-controlled transient elastography in the absence of other causes of chronic liver disease. OR and 95 % CI were estimated using logistic regression. Participants with daily eating window of ≤ 8 h had lower odds of NAFLD (OR = 0·70, 95 % CI: 0·52, 0·93), compared with those with ≥ 10 h window. Early (05.00-15.00) and late TRE (11.00-21.00) showed inverse associations with NAFLD prevalence without statistical heterogeneity (Pheterogeneity = 0·649) with OR of 0·73 (95 % CI: 0·36, 1·47) and 0·61 (95 % CI: 0·44, 0·84), respectively. Such inverse association seemed stronger in participants with lower energy intake (OR = 0·58, 95 % CI: 0·38, 0·89, Pinteraction = 0·020). There are no statistical differences in the TRE-NAFLD associations according to physical activity (Pinteraction = 0·390) or diet quality (Pinteraction = 0·110). TRE might be associated with lower likelihood of NAFLD. Such inverse association is independent of physical activity and diet quality and appears stronger in individuals consuming lower energy. Given the potential misclassification of TRE based on one- or two-day recall in the analysis, epidemiological studies with validated methods for measuring the habitual timing of dietary intake are warranted.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article