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TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis.
Yang, Wen-Ji; Han, Fang-Hui; Gu, Yi-Pei; Qu, Hui; Liu, Jia; Shen, Jian-Hua; Leng, Ying.
Afiliação
  • Yang WJ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Han FH; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Gu YP; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Qu H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Liu J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Shen JH; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Leng Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. jhshen@simm.ac.cn.
Acta Pharmacol Sin ; 44(8): 1649-1664, 2023 Aug.
Article em En | MEDLINE | ID: mdl-36997665
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Colite Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Colite Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article