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Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms.
Benson, Tyler W; Conrad, Kelsey A; Li, Xinmin S; Wang, Zeneng; Helsley, Robert N; Schugar, Rebecca C; Coughlin, Taylor M; Wadding-Lee, Caris; Fleifil, Salma; Russell, Hannah M; Stone, Timothy; Brooks, Michael; Buffa, Jennifer A; Mani, Kevin; Björck, Martin; Wanhainen, Anders; Sangwan, Naseer; Biddinger, Sudha; Bhandari, Rohan; Ademoya, Akiirayi; Pascual, Crystal; Tang, W H Wilson; Tranter, Michael; Cameron, Scott J; Brown, J Mark; Hazen, Stanley L; Owens, A Phillip.
Afiliação
  • Benson TW; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Conrad KA; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Li XS; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Wang Z; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Helsley RN; Pathobiology and Molecular Medicine Graduate Program (K.A.C., T.M.C., C.W.-L., H.M.R., M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Schugar RC; Department of Cardiovascular and Metabolic Sciences, Learner Research Institute (X.S.L., Z.W., R.N.H., R.C.S., J.A.B., N.S., R.B., A.A., C.P., W.H.W.T., S.J.C., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Coughlin TM; Center for Microbiome & Human Health (X.S.L., Z.W., J.A.B., N.S., W.H.W.T., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Wadding-Lee C; Department of Cardiovascular and Metabolic Sciences, Learner Research Institute (X.S.L., Z.W., R.N.H., R.C.S., J.A.B., N.S., R.B., A.A., C.P., W.H.W.T., S.J.C., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Fleifil S; Center for Microbiome & Human Health (X.S.L., Z.W., J.A.B., N.S., W.H.W.T., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Russell HM; Department of Cardiovascular and Metabolic Sciences, Learner Research Institute (X.S.L., Z.W., R.N.H., R.C.S., J.A.B., N.S., R.B., A.A., C.P., W.H.W.T., S.J.C., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Stone T; Department of Cardiovascular and Metabolic Sciences, Learner Research Institute (X.S.L., Z.W., R.N.H., R.C.S., J.A.B., N.S., R.B., A.A., C.P., W.H.W.T., S.J.C., J.M.B., S.L.H.), Cleveland Clinic, OH.
  • Brooks M; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Buffa JA; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Mani K; Pathobiology and Molecular Medicine Graduate Program (K.A.C., T.M.C., C.W.-L., H.M.R., M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Björck M; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Wanhainen A; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Sangwan N; Pathobiology and Molecular Medicine Graduate Program (K.A.C., T.M.C., C.W.-L., H.M.R., M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Biddinger S; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Bhandari R; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Ademoya A; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Pascual C; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Tang WHW; Pathobiology and Molecular Medicine Graduate Program (K.A.C., T.M.C., C.W.-L., H.M.R., M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Tranter M; Department of Environmental Health (T.S.), University of Cincinnati College of Medicine, OH.
  • Cameron SJ; Division of Biostatistics and Bioinformatics (T.S.), University of Cincinnati College of Medicine, OH.
  • Brown JM; Department of Internal Medicine (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Hazen SL; Division of Cardiovascular Health & Disease (T.W.B., K.A.C., T.M.C., C.W.-L., S.F., H.M.R., M. Brooks, M.T., A.P.O.), University of Cincinnati College of Medicine, OH.
  • Owens AP; Department of Cardiovascular and Metabolic Sciences, Learner Research Institute (X.S.L., Z.W., R.N.H., R.C.S., J.A.B., N.S., R.B., A.A., C.P., W.H.W.T., S.J.C., J.M.B., S.L.H.), Cleveland Clinic, OH.
Circulation ; 147(14): 1079-1096, 2023 04 04.
Article em En | MEDLINE | ID: mdl-37011073
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Abdominal / Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Abdominal / Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article