Formulation, and optimization of transdermal Atorvastatin Calcium-Loaded Ultra-flexible vesicles; ameliorates poloxamer 407-caused dyslipidemia.

Akl, Mohamed A; Ryad, Sherif; Ibrahim, Mohamed F; Kassem, Alaa A

Akl, Mohamed A; Ryad, Sherif; Ibrahim, Mohamed F; Kassem, Alaa A.

Afiliação

Akl MA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt; Department of Pharmaceutics, Faculty of Pharmacy, The Islamic University, Najaf 54001, Iraq. Electronic address: mohamedakl@Azhar.edu.eg.
Ryad S; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt.
Ibrahim MF; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt.
Kassem AA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt.

Int J Pharm ; 638: 122917, 2023 May 10.

Article em En | MEDLINE | ID: mdl-37019321

Assuntos

Dislipidemias; Poloxâmero; Ratos; Animais; Administração Cutânea; Atorvastatina/farmacologia; Sistemas de Liberação de Medicamentos/métodos; Ratos Wistar; Pele/metabolismo; Lecitinas/metabolismo; Dislipidemias/tratamento farmacológico; Dislipidemias/metabolismo; Disponibilidade Biológica; Tamanho da Partícula

Palavras-chave

Atorvastatin Calcium; Dyslipidemia; Thin film hydration method; Transdermal delivery; Transferosome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poloxâmero / Dislipidemias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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