High-throughput screening of mutations affecting SARS-CoV-2 spike functions.
Trends Immunol
; 44(5): 321-323, 2023 05.
Article
em En
| MEDLINE
| ID: mdl-37031063
ABSTRACT
The spike (S) protein of SARS-CoV-2, which is undergoing rapid evolution, plays crucial roles in viral immune escape, infectivity, and transmissibility. To gain clinical insight, Dadonaite et al. developed a novel deep mutational scanning (DMS) platform for mapping the effects of S protein mutations on immune evasion and viral infectivity.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ensaios de Triagem em Larga Escala
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article