A new terrein dimer and a new meroterpene from the mangrove endophytic fungus Lichtheimia sp.
J Asian Nat Prod Res
; 25(11): 1068-1075, 2023 Nov.
Article
em En
| MEDLINE
| ID: mdl-37042744
ABSTRACT
A new terrein dimer named lichtheicol A (1) and a new meroterpene named lichtheiterpene A (2), were isolated from the mangrove endophytic fungus Lichtheimia sp. J2B1, together with 10 known compounds (3-12). The planar structures and absolute configurations of 1 and 2 were established by a combination of extensive spectroscopic data analyses and electronic circular dichroism (ECD) calculations. Compounds 4 and 5 exhibited marked inhibitory effects against butyrylcholinesterase (BuChE) with IC50 values of 0.71 and 0.53 µM, respectively.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Butirilcolinesterase
/
Fungos
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article