NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-&#954;B signaling in human periodontal ligament cells.

Yi, Xiaowei; Song, Yao; Xu, Jialei; Wang, Liu; Liu, Liu; Huang, Dingming; Zhang, Lan

NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-κB signaling in human periodontal ligament cells.

Yi, Xiaowei; Song, Yao; Xu, Jialei; Wang, Liu; Liu, Liu; Huang, Dingming; Zhang, Lan.

Afiliação

Yi X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Song Y; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Xu J; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Wang L; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Liu L; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Huang D; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China.
Zhang L; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 14# Third Section, Renmin Nan Road, Chengdu, 610041, China. zlnancy914@sina.com.

Odontology ; 112(1): 100-111, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37043073

Assuntos

Inflamassomos; NF-kappa B; Humanos; NF-kappa B/metabolismo; Inflamassomos/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Ligamento Periodontal; Estresse Oxidativo; Inflamação; Citocinas/metabolismo; Proteínas NLR/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Proteínas Reguladoras de Apoptose/metabolismo; Proteínas com Motivo Tripartido/metabolismo

Palavras-chave

Diabetes; Innate immunity; NLRP10; NLRs; Periodontitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Inflamassomos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Inflamassomos Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article