Your browser doesn't support javascript.
loading
Association of primary lifetime occupational cognitive complexity and cognitive decline in a diverse cohort: Results from the KHANDLE study.
Soh, Yenee; Eng, Chloe W; Mayeda, Elizabeth Rose; Whitmer, Rachel A; Lee, Catherine; Peterson, Rachel L; Mungas, Dan M; Glymour, M Maria; Gilsanz, Paola.
Afiliação
  • Soh Y; Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.
  • Eng CW; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
  • Mayeda ER; Department of Epidemiology and Population Health, Stanford University, Stanford, California, USA.
  • Whitmer RA; Department of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
  • Lee C; Department of Neurology, School of Medicine, University of California, Davis, Davis, California, USA.
  • Peterson RL; Department of Public Health Sciences, University of California, Davis, Davis, California, USA.
  • Mungas DM; Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.
  • Glymour MM; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.
  • Gilsanz P; School of Public and Community Health Sciences, University of Montana, Missoula, Montana, USA.
Alzheimers Dement ; 19(9): 3926-3935, 2023 09.
Article em En | MEDLINE | ID: mdl-37057753
INTRODUCTION: Higher occupational complexity has been linked to favorable cognitive outcomes, but rarely examined in racially and ethnically diverse populations. METHODS: In a diverse cohort (n = 1536), linear mixed-effects models estimated associations between main lifetime occupational complexity and domain-specific cognitive decline (z-standardized). Occupational complexity with data, people, and things were classified using the Dictionary of Occupational Titles. RESULTS: For occupational complexity with data, highest tertile (vs. lowest) was associated with higher baseline executive function (ß = 0.11; 95% confidence interval [CI] 0.00-0.22) and slower annual rate of decline (ß = 0.03; 95% CI 0.01-0.06), and higher baseline semantic memory (ß = 0.14; 95% CI 0.04-0.25). Highest tertile of occupational complexity with people was associated with higher baseline executive function (ß = 0.29; 95% CI 0.18-0.40), verbal episodic memory (ß = 0.12; 95% CI 0.00-0.24), and semantic memory (ß = 0.23; 95% CI 0.12-0.34). DISCUSSION: In a diverse cohort, higher occupational complexity is associated with better cognition. Findings should be verified in larger cohorts. HIGHLIGHT: Few studies have examined associations of occupational complexity with cognition in diverse populations. Racial and ethnic minorities are disproportionately exposed to lower occupational complexity. Occupational complexity with data and people are associated with better cognition.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Disfunção Cognitiva Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Disfunção Cognitiva Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article