Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers.

Edwina, Angela Elma; Koch, Birgit C P; Muller, Anouk E; Al Jalali, Valentin; Matzneller, Peter; Zeitlinger, Markus; Sassen, Sebastiaan D T

Edwina, Angela Elma; Koch, Birgit C P; Muller, Anouk E; Al Jalali, Valentin; Matzneller, Peter; Zeitlinger, Markus; Sassen, Sebastiaan D T.

Afiliação

Edwina AE; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Koch BCP; Rotterdam Clinical Pharmacometrics Group, Rotterdam, The Netherlands.
Muller AE; Gerontology and Geriatrics Unit, Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.
Al Jalali V; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
Matzneller P; Rotterdam Clinical Pharmacometrics Group, Rotterdam, The Netherlands.
Zeitlinger M; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands.
Sassen SDT; Department of Medical Microbiology, Haaglanden Medical Center, The Hague, The Netherlands.

Eur J Clin Pharmacol ; 79(6): 775-787, 2023 Jun.

Article em En | MEDLINE | ID: mdl-37060459

Assuntos

Fosfomicina; Masculino; Humanos; Fosfomicina/farmacologia; Estudos Cross-Over; Voluntários Saudáveis; Antibacterianos; Escherichia coli; Testes de Sensibilidade Microbiana; Método de Monte Carlo

Palavras-chave

Antimicrobial; Escherichia coli; Fosfomycin; Population pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfomicina Tipo de estudo: Clinical_trials / Health_economic_evaluation Limite: Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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