Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.

DeBlasi, Janine M; Falzone, Aimee; Caldwell, Samantha; Prieto-Farigua, Nicolas; Prigge, Justin R; Schmidt, Edward E; Chio, Iok In Christine; Karreth, Florian A; DeNicola, Gina M

DeBlasi, Janine M; Falzone, Aimee; Caldwell, Samantha; Prieto-Farigua, Nicolas; Prigge, Justin R; Schmidt, Edward E; Chio, Iok In Christine; Karreth, Florian A; DeNicola, Gina M.

Afiliação

DeBlasi JM; Department of Metabolism & Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Falzone A; Cancer Biology PhD Program, University of South Florida, Tampa, Florida.
Caldwell S; Department of Metabolism & Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Prieto-Farigua N; Department of Metabolism & Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Prigge JR; Department of Metabolism & Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Schmidt EE; Microbiology & Cell Biology Department, Montana State University, Bozeman, Montana.
Chio IIC; Microbiology & Cell Biology Department, Montana State University, Bozeman, Montana.
Karreth FA; Department of Genetics and Development, Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, New York.
DeNicola GM; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.

Cancer Res ; 83(12): 1953-1967, 2023 06 15.

Article em En | MEDLINE | ID: mdl-37062029

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Transdução de Sinais; Animais; Humanos; Camundongos; Carcinogênese/genética; Carcinoma Pulmonar de Células não Pequenas/patologia; Linhagem Celular Tumoral; Proteína 1 Associada a ECH Semelhante a Kelch/genética; Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Pulmão/patologia; Neoplasias Pulmonares/patologia; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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