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Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Kumar, Hirdesh; Williford, Emily E; Blake, Kevin S; Virgin-Downey, Brett; Dantas, Gautam; Wencewicz, Timothy A; Tolia, Niraj H.
Afiliação
  • Kumar H; Host-pathogen interaction and structural vaccinology section (HPISV), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Williford EE; Department of Chemistry, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.
  • Blake KS; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA.
  • Virgin-Downey B; Department of Chemistry, Washington University in St. Louis, One Brookings Drive, St. Louis, MO, 63130, USA.
  • Dantas G; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA. dantas@wustl.edu.
  • Wencewicz TA; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, MO, USA. dantas@wustl.edu.
  • Tolia NH; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. dantas@wustl.edu.
Commun Biol ; 6(1): 423, 2023 04 17.
Article em En | MEDLINE | ID: mdl-37062778

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetraciclina / Tetraciclinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetraciclina / Tetraciclinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article