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30 Jahre Nanobodies: Neues von kleinen Helfern mit großem Potenzial.
Wagner, Teresa R; Burgstaller, Sandra; Frecot, Desiree I; Lukowski, Robert; Rothbauer, Ulrich.
Afiliação
  • Wagner TR; Pharmazeutische Biotechnologie, Universität Tübingen, Tübingen, Deutschland.
  • Burgstaller S; NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Pharmazeutische Biotechnologie, Markwiesenstraße 55, D-72770 Reutlingen, Deutschland.
  • Frecot DI; Pharmazeutische Biotechnologie, Universität Tübingen, Tübingen, Deutschland.
  • Lukowski R; Pharmakologie, Toxikologie und Klinische Pharmazie, Universität Tübingen, Tübingen, Deutschland.
  • Rothbauer U; Pharmazeutische Biotechnologie, Universität Tübingen, Tübingen, Deutschland.
Biospektrum (Heidelb) ; 29(2): 145-149, 2023.
Article em De | MEDLINE | ID: mdl-37073321
ABSTRACT
2023 marks the 30th anniversary of the discovery of single-domain antibody fragments in camelids, better known as nanobodies. This was the starting point for their tremendous success story in biomedicine. Here we highlight recent advances in the development of nanobodies for the detection of neutralizing SARS-CoV-2 antibodies, as biosensors for monitoring extracellular metabolites and as tracer molecules for non-invasive imaging of immune cells.

Texto completo: 1 Base de dados: MEDLINE Idioma: De Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: De Ano de publicação: 2023 Tipo de documento: Article