The programmed cell death protein 1 (PD1) and the programmed cell death ligand 1 (PD-L1) are significantly downregulated on macrophages and Hofbauer cells in the placenta of preeclampsia patients.

Mittelberger, Johanna; Seefried, Marina; Löb, Sanja; Kuhn, Christina; Franitza, Manuela; Garrido, Fabian; Wild, Carl Mathis; Ditsch, Nina; Jeschke, Udo; Dannecker, Christian

Mittelberger, Johanna; Seefried, Marina; Löb, Sanja; Kuhn, Christina; Franitza, Manuela; Garrido, Fabian; Wild, Carl Mathis; Ditsch, Nina; Jeschke, Udo; Dannecker, Christian.

Afiliação

Mittelberger J; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Seefried M; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Löb S; Department of Obstetrics and Gynecology, University Hospital, University of Wuerzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.
Kuhn C; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Franitza M; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Garrido F; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Wild CM; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Ditsch N; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.
Jeschke U; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany. Electronic address: udo.jeschke@med.uni-augsburg.de.
Dannecker C; Department of Obstetrics and Gynecology, University Hospital Augsburg, Stenglinstraße 2, 86156 Augsburg, Germany.

J Reprod Immunol ; 157: 103949, 2023 06.

Article em En | MEDLINE | ID: mdl-37079975

Assuntos

Pré-Eclâmpsia; Receptor de Morte Celular Programada 1; Feminino; Humanos; Masculino; Gravidez; Apoptose; Antígeno B7-H1/metabolismo; Vilosidades Coriônicas/metabolismo; Ligantes; Macrófagos; Pré-Eclâmpsia/metabolismo; Receptor de Morte Celular Programada 1/metabolismo

Palavras-chave

Immune checkpoints; Macrophages; PD-L1; PD1; Preeclampsia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Receptor de Morte Celular Programada 1 Limite: Female / Humans / Male / Pregnancy Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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