ctDNA Monitoring for Small Cell Lung Cancer: Ready for Prime Time?

Pellini, Bruna; Chaudhuri, Aadel A

Pellini, Bruna; Chaudhuri, Aadel A.

Afiliação

Pellini B; Department of Thoracic Oncology, Moffitt Cancer Center and Research Institute, Tampa, Florida.
Chaudhuri AA; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida.

Clin Cancer Res ; 29(12): 2176-2178, 2023 06 13.

Article em En | MEDLINE | ID: mdl-37097069

ABSTRACT

ABSTRACT

Small cell lung cancer (SCLC) is the deadliest form of lung cancer and has few precision medicine approaches available. A recent study analyzed circulating tumor DNA (ctDNA) in 33 patients with extensive-stage SCLC and showed that ctDNA levels and response patterns correlate strongly with clinical response and survival outcomes. See related article by Sivapalan et al., p. 2310.

Assuntos

Ácidos Nucleicos Livres; DNA Tumoral Circulante; Neoplasias Pulmonares; Carcinoma de Pequenas Células do Pulmão; Humanos; Mutação; Neoplasias Pulmonares/genética; DNA Tumoral Circulante/genética; Biomarcadores Tumorais/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Pequenas Células do Pulmão / Ácidos Nucleicos Livres / DNA Tumoral Circulante / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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