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Synchronous gastric MALT lymphoma and gastric adenocarcinoma of fundic gland type arising from a hamartomatous inverted polyp in a Helicobacter pylori naive patient.
Miyamoto, Ryo; Takigawa, Hidehiko; Kotachi, Takahiro; Kadota, Hiroki; Yuge, Ryo; Hayashi, Ryohei; Urabe, Yuji; Ishikawa, Akira; Sentani, Kazuhiro; Oka, Shiro.
Afiliação
  • Miyamoto R; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
  • Takigawa H; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan. hidehiko@hiroshima-u.ac.jp.
  • Kotachi T; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
  • Kadota H; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
  • Yuge R; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
  • Hayashi R; Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.
  • Urabe Y; Department of Gastrointestinal Endoscopy and Medicine, Hiroshima University Hospital, Hiroshima, Japan.
  • Ishikawa A; Department of Molecular Pathology, Hiroshima University Hospital, Hiroshima, Japan.
  • Sentani K; Department of Molecular Pathology, Hiroshima University Hospital, Hiroshima, Japan.
  • Oka S; Department of Gastroenterology, Hiroshima University Hospital, Hiroshima, 734-8553, Japan.
Clin J Gastroenterol ; 16(4): 521-526, 2023 Aug.
Article em En | MEDLINE | ID: mdl-37099238
ABSTRACT
We present a rare case that showed the coexistence of gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma in Helicobacter pylori-naive stomach. A 72-year-old man was followed up after surgery for epithelial carcinoma of the glottis at the Department of Otolaryngology. He underwent an upper gastrointestinal endoscopy for an abnormal PET-CT accumulation, which revealed gastric adenocarcinoma of fundic gland type in the gastric fundus and MALT lymphoma in the upper gastric body. Hence, we performed an endoscopic submucosal dissection for gastric cancer and diagnosed gastric adenocarcinoma of fundic gland type derived from a hamartomatous-inverted polyp. Subsequently, Gastric MALT lymphoma was treated with radiation therapy because the API2-MALT1 gene was positive and the Helicobacter pylori infection was negative. A complete response was observed. Even in Hp-naive stomachs, cases such as the present case are complicated by special types of gastric cancer and MALT lymphoma, and endoscopic examination should be performed with these diseases in mind.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Adenocarcinoma / Helicobacter pylori / Infecções por Helicobacter / Linfoma de Zona Marginal Tipo Células B Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Adenocarcinoma / Helicobacter pylori / Infecções por Helicobacter / Linfoma de Zona Marginal Tipo Células B Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article