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Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection.
Vu, Michelle N; Alvarado, R Elias; Morris, Dorothea R; Lokugamage, Kumari G; Zhou, Yiyang; Morgan, Angelica L; Estes, Leah K; McLeland, Alyssa M; Schindewolf, Craig; Plante, Jessica A; Ahearn, Yani P; Meyers, William M; Murray, Jordan T; Crocquet-Valdes, Patricia A; Weaver, Scott C; Walker, David H; Russell, William K; Routh, Andrew L; Plante, Kenneth S; Menachery, Vineet.
Afiliação
  • Vu MN; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Alvarado RE; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Morris DR; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, United States.
  • Lokugamage KG; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Zhou Y; Pediatrics, University of Texas Medical Branch, Galveston, TX, United States.
  • Morgan AL; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Estes LK; Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States.
  • McLeland AM; Pathology, University of Texas Medical Branch, Galveston, TX, United States.
  • Schindewolf C; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Plante JA; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Ahearn YP; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Meyers WM; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Murray JT; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, United States.
  • Crocquet-Valdes PA; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, United States.
  • Weaver SC; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Walker DH; Pathology, University of Texas Medical Branch, Galveston, TX, United States.
  • Russell WK; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Routh AL; Pathology, University of Texas Medical Branch, Galveston, TX, United States.
  • Plante KS; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
  • Menachery V; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, United States.
bioRxiv ; 2023 Jul 10.
Article em En | MEDLINE | ID: mdl-37131784

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article