Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages.

Zhang, Ruiyi; Dong, Yifei; Liu, Yang; Moezzi, Dorsa; Ghorbani, Samira; Mirzaei, Reza; Lozinski, Brian M; Dunn, Jeff F; Yong, V Wee; Xue, Mengzhou

Zhang, Ruiyi; Dong, Yifei; Liu, Yang; Moezzi, Dorsa; Ghorbani, Samira; Mirzaei, Reza; Lozinski, Brian M; Dunn, Jeff F; Yong, V Wee; Xue, Mengzhou.

Afiliação

Zhang R; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Dong Y; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
Liu Y; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Moezzi D; Department of Biochemistry, Microbiology, & Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Ghorbani S; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Mirzaei R; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
Lozinski BM; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Dunn JF; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Yong VW; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Xue M; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.

Stroke Vasc Neurol ; 8(6): 486-502, 2023 12 29.

Article em En | MEDLINE | ID: mdl-37137522

Assuntos

Lesões Encefálicas; Microglia; Camundongos; Animais; Receptores X do Fígado/agonistas; Receptores X do Fígado/metabolismo; Microglia/metabolismo; Receptores Nucleares Órfãos/agonistas; Receptores Nucleares Órfãos/metabolismo; Imagem de Tensor de Difusão; Macrófagos/metabolismo; Colesterol/metabolismo; Colesterol/farmacologia; Hemorragia Cerebral/metabolismo; Inflamação; Lesões Encefálicas/metabolismo; Hematoma

Palavras-chave

hemorrhage; inflammatory response; stroke

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lesões Encefálicas / Microglia Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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