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E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1.
Zhang, Nannan; Gao, Xiaoliang; Yuan, Qiangqiang; Fu, Xin; Wang, Pengliang; Cai, Fenglin; Liu, Hui; Zhang, Jing; Liang, Han; Nie, Yongzhan; Deng, Jingyu.
Afiliação
  • Zhang N; State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.
  • Gao X; Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
  • Yuan Q; State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.
  • Fu X; State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.
  • Wang P; Guangxi Medical University, Nanning, 530021, Guangxi, China.
  • Cai F; Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
  • Liu H; Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
  • Zhang J; College of Life Sciences, Northwest University, Xi'an, 710069, China.
  • Liang H; College of Life Sciences, Northwest University, Xi'an, 710069, China.
  • Nie Y; Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
  • Deng J; State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China. yongznie@fmmu.edu.cn.
Clin Epigenetics ; 15(1): 77, 2023 05 05.
Article em En | MEDLINE | ID: mdl-37147733

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Ubiquitina-Proteína Ligases / DNA (Citosina-5-)-Metiltransferase 1 / Protocaderinas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Ubiquitina-Proteína Ligases / DNA (Citosina-5-)-Metiltransferase 1 / Protocaderinas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article