[Immune function and research progress of pentraxin 3 in pulmonary infectious diseases].
Zhonghua Jie He He Hu Xi Za Zhi
; 46(5): 517-520, 2023 May 12.
Article
em Zh
| MEDLINE
| ID: mdl-37147817
ABSTRACT
Pentraxins3 (PTX3) is an acute-phase protein of the pentraxin family that is synthetized and stored in a variety of cells. As an important mediator of innate immunity, PTX3 is rapidly released during microbial invasion and inflammatory response. It promotes the recognition of pathogens by myeloid cells through regulating complement activation. Recent studies have indicated that PTX3 concentrations in peripheral blood or tissues increase rapidly after infection, and the increased level is associated with the severity of the disease. Thus, PTX3 appears to be a vital clinical biomarker in the diagnosis and prognosis of pulmonary infectious diseases.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Transmissíveis
/
Inflamação
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article