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Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.
Liang, Shun-Qing; Liu, Pengpeng; Ponnienselvan, Karthikeyan; Suresh, Sneha; Chen, Zexiang; Kramme, Christian; Chatterjee, Pranam; Zhu, Lihua Julie; Sontheimer, Erik J; Xue, Wen; Wolfe, Scot A.
Afiliação
  • Liang SQ; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.
  • Liu P; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Pengpeng.Liu2@umassmed.edu.
  • Ponnienselvan K; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
  • Suresh S; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
  • Chen Z; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.
  • Kramme C; Wyss Institute, Harvard Medical School, Boston, MA, USA.
  • Chatterjee P; Wyss Institute, Harvard Medical School, Boston, MA, USA.
  • Zhu LJ; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Sontheimer EJ; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Xue W; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
  • Wolfe SA; Department of Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Nat Methods ; 20(6): 898-907, 2023 Jun.
Article em En | MEDLINE | ID: mdl-37156841
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Edição de Genes Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Edição de Genes Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article